A-Level Biology OCR Notes

3.1.2 Transport in animals

Mass Transport in Animals
  • Red blood cells transport oxygen using the protein haemoglobin
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  • Haemoglobin is made up of four polypeptide chains, each containing a prosthetic haem group. Each haem group binds one oxygen molecule
  • Haemoglobin saturation depends on the partial pressure of oxygen (pO2). Binding of the first O2 molecule causes a conformational change in the haemoglobin, making the haem groups more accessible to oxygen.
  • ​Fetal haemoglobin has a higher oxygen affinity than adult haemoglobin because fetal haemoglobin must be able to bind oxygen from adult haemoglobin in the placenta.
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  • Carbon dioxide is transported in the blood for release from the lungs.
    • 5% of the carbon dioxide transported is dissolved in the blood plasma
    • 10% of the carbon dioxide transported is combined with haemoglobin to form carbaminohaemoglobin
    • ​85% is transported as hydrogencarbonate ions (HCCO3-) dissolved in blood plasma
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  • ​Bohr affect- haemoglobin’s oxygen binding affinity is inversely related to the concentration of carbon dioxide, causing the oxygen dissociation curve to shift
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  • A good transport system has
    • A fluid medium to transport substances
    • A pump to create pressure for the circulation of the transport fluid
    • Exchange surfaces
  • An open circulatory system is one in which the blood is not held in vessels e.g. in insects.
  • A close circulatory system the blood is contained within vessels.
  • A single circulatory system the blood flows through the heart once for each circuit of the body.
  • A double circulatory system blood within double circulatory systems flows through the heart twice for each circuit of the body
  • Circulatory system:
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​The Heart
  • The cardiac cycle is the sequence of events that occur within one full beat of the heart.
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  • Systole is the contraction stage and diastole is the relaxation stage
  • Cardiac muscle is myogenic, meaning it can contract and relax without receiving signals from the nervous system
  • The sinoatrial node (SAN) sends out regular waves of electrical activity to the left & right atrial wall causing contraction. The electrical waves are then passed onto the atrioventricular node (AVN), then to the bundle of His, with a slight delay. The bundle of His splits into the Purkynge tissue, causing contraction of the left & right ventricles from the bottom up.
  • The rate at which the SAN fires is controlled unconsciously by the medulla oblongata in the autonomic nervous system
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  • ECGs can detect the electrical signals through the skin
    • P wave shows atrial systole
    • QRS complex shows ventricular contraction
    • T wave shows diastole
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  • Bradycardia- slow heart rate:
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  • Tachycardia- fast heart rate:
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  • Atrial fibrillation- atria beats more rapidly than the ventricles:
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  • Ectopia- irregular heartbeat:
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